TREE4NB Training, Reorganizing, Evaluating, Enabling for Natural Project co-financed by the European Union, the Italian State and Regione Campania, as part of the POR Campania ERDF 2014-2020 with a subsidy in the form of a grant The research and development project, with code 18016BP000000017, is aimed at optimizing the efficiency and effectiveness of health expense of public and private healthcare facilities in Regione Campania, through an innovative model of re-engineering of social and health processes, to be translated into an innovative ICT solution of Big Data Analytics for clinical decision support and governance and the strengthening of patient empowerment, through forecast assessments of risk assessment derived from a correlation process of information, coming from clinical and extra-clinical datasets and based on Machine Learning and Artificial Intelligence algorithms. …